| Name | Ticker | Relationship | Date | Transaction | AVG Cost Per Share | Shares | Total Value | Securities Owned After Transaction(s) | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| Geary Richard S | IONS | EVP, Chief Development Officer | Nov 6 '25 | Sell | $75.76 | 33,038 | $2,501,724.83 | 59,657 | |
| Geary Richard S | IONS | EVP, Chief Development Officer | Nov 5 '25 | Sell | $75.01 | 1,601 | $120,091.01 | 59,657 | |
| Geary Richard S | IONS | EVP, Chief Development Officer | Nov 3 '25 | Sell | $75.05 | 1,680 | $126,090.72 | 59,657 | |
| Geary Richard S | IONS | EVP, Chief Development Officer | Oct 31 '25 | Sell | $75.11 | 89,249 | $6,703,340.67 | 59,657 |