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as 10-24-2025 3:51pm EST

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Health Care

Biotechnology: Pharmaceutical Preparations

Nasdaq

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.

Founded: 1989 Country:
United States
United States
Employees: N/A City: CARLSBAD
Market Cap: 6.8B IPO Year: 1991
Target Price: $75.55 AVG Volume (30 days): 2.1M
Analyst Decision: Strong Buy Number of Analysts: 20
Dividend Yield:
N/A
Dividend Payout Frequency: N/A
EPS: -1.73 EPS Growth: N/A
52 Week Low/High: $23.95 - $74.42 Next Earning Date: 10-29-2025
Revenue: $944,050,000 Revenue Growth: 16.05%
Revenue Growth (this year): 24.02% Revenue Growth (next year): 4.06%

IONS Daily Stock ML Predictions

Stock Insider Trading Activity of Ionis Pharmaceuticals Inc. (IONS)

Name Ticker Relationship Date Transaction AVG Cost Per Share Shares Total Value Securities Owned After Transaction(s) SEC Form 4
Swayze Eric IONS EVP Research Oct 16 '25 Sell $73.62 53 $3,901.93 256
Devers Shannon L. IONS EVP, Chief Human Resources Ofc Oct 16 '25 Sell $73.62 1,263 $92,983.70 17,494
Birchler Brian IONS EVP, Corp and Development Ops Oct 15 '25 Sell $72.23 12,425 $897,398.11 56,826
PARSHALL B LYNNE IONS Director Oct 15 '25 Sell $71.74 5,000 $358,721.50 61,344
Devers Shannon L. IONS EVP, Chief Human Resources Ofc Oct 15 '25 Sell $72.94 6,000 $437,653.80 17,494
Birchler Brian IONS EVP, Corp and Development Ops Oct 14 '25 Sell $72.03 11,475 $826,589.00 56,826
Baroldi Joseph IONS EVP, Chief Business Officer Oct 6 '25 Sell $69.37 1,625 $112,725.11 30,301
Swayze Eric IONS EVP Research Oct 6 '25 Sell $69.02 6,849 $472,717.98 256
Monia Brett P IONS Chief Executive Officer Oct 6 '25 Sell $69.26 437 $30,268.24 179,572
O'NEIL PATRICK R. IONS EVP CLO & General Counsel Oct 6 '25 Sell $69.58 13,441 $937,337.63 57,130

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