| Name | Ticker | Relationship | Date | Transaction | AVG Cost Per Share | Shares | Total Value | Securities Owned After Transaction(s) | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| Birchler Brian | IONS | EVP, Corp and Development Ops | Oct 15 '25 | Sell | $72.23 | 12,425 | $897,398.11 | 56,826 | |
| Birchler Brian | IONS | EVP, Corp and Development Ops | Oct 14 '25 | Sell | $72.03 | 11,475 | $826,589.00 | 56,826 |