| Name | Ticker | Relationship | Date | Transaction | AVG Cost Per Share | Shares | Total Value | Securities Owned After Transaction(s) | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| Baroldi Joseph | IONS | EVP, Chief Business Officer | Oct 6 '25 | Sell | $69.37 | 1,625 | $112,725.11 | 30,301 | |
| Baroldi Joseph | IONS | EVP, Chief Business Officer | Oct 2 '25 | Sell | $68.01 | 15,000 | $1,020,210.00 | 30,301 |