as of 02-12-2026 11:20am EST
Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.
| Founded: | 2013 | Country: | United States |
| Employees: | N/A | City: | CAMBRIDGE |
| Market Cap: | 129.6M | IPO Year: | 2017 |
| Target Price: | N/A | AVG Volume (30 days): | 344.4K |
| Analyst Decision: | N/A | Number of Analysts: | N/A |
| Dividend Yield: | N/A | Dividend Payout Frequency: | N/A |
| EPS: | -0.79 | EPS Growth: | N/A |
| 52 Week Low/High: | $0.51 - $3.22 | Next Earning Date: | 03-26-2026 |
| Revenue: | $40,549,000 | Revenue Growth: | -61.91% |
| Revenue Growth (this year): | -45.79% | Revenue Growth (next year): | -96.86% |
| P/E Ratio: | N/A | Index: | N/A |
| Free Cash Flow: | -27674000.0 | FCF Growth: | N/A |
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Chief Operating Officer
Avg Cost/Share
$2.36
Shares
18,652
Total Value
$44,018.72
Owned After
742,506
SEC Form 4
See Remarks
Avg Cost/Share
$2.36
Shares
87,917
Total Value
$207,484.12
Owned After
1,062,907
Chief Operating Officer
Avg Cost/Share
$2.24
Shares
3,471
Total Value
$7,775.04
Owned After
742,506
SEC Form 4
Chief Operating Officer
Avg Cost/Share
$2.14
Shares
24,224
Total Value
$51,839.36
Owned After
742,506
SEC Form 4
Chief Operating Officer
Avg Cost/Share
$2.20
Shares
18,891
Total Value
$41,560.20
Owned After
742,506
SEC Form 4
See Remarks
Avg Cost/Share
$2.20
Shares
18,442
Total Value
$40,572.40
Owned After
1,062,907
SEC Form 4
| Insider | Ticker | Relationship | Date | Transaction | Avg Cost | Shares | Total Value | Owned After | SEC Forms |
|---|---|---|---|---|---|---|---|---|---|
| Keutzer Timothy | SPRO | Chief Operating Officer | Feb 6, 2026 | Sell | $2.36 | 18,652 | $44,018.72 | 742,506 | |
| Rajavelu Esther | SPRO | See Remarks | Feb 6, 2026 | Sell | $2.36 | 87,917 | $207,484.12 | 1,062,907 | |
| Keutzer Timothy | SPRO | Chief Operating Officer | Feb 4, 2026 | Sell | $2.24 | 3,471 | $7,775.04 | 742,506 | |
| Keutzer Timothy | SPRO | Chief Operating Officer | Feb 3, 2026 | Sell | $2.14 | 24,224 | $51,839.36 | 742,506 | |
| Keutzer Timothy | SPRO | Chief Operating Officer | Feb 2, 2026 | Sell | $2.20 | 18,891 | $41,560.20 | 742,506 | |
| Rajavelu Esther | SPRO | See Remarks | Feb 2, 2026 | Sell | $2.20 | 18,442 | $40,572.40 | 1,062,907 |
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