SNES

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Exhibit 99.1

SenesTech Reports Record Preliminary Third Quarter Revenue Exceeding $1 Million, the Highest in Company History,

with 40% Sequential Growth

Preliminary Revenue of $1.1 Million is the Highest Quarterly Revenue in the Company’s History

SURPRISE, Ariz., Oct. 15, 2026 — SenesTech, Inc. (NASDAQ: SNES), the leader in rodent birth control and sustainable rodent population management, today announced preliminary revenue results for the third quarter of 2026. The Company plans to release its definitive third quarter financial results the week of November 9, 2026.

Preliminary third quarter 2026 revenue was approximately $1.1 million, representing approximately 40% growth compared with the second quarter of 2026 and approximately 55% growth compared with the third quarter of 2025. It was also the Company’s first quarter at or above the $1 million revenue threshold, a key milestone.

The Company expects its definitive third quarter financial results to reflect continued momentum in e-commerce, including higher subscription revenue, which is expanding the recurring component of SenesTech’s revenue base, as well as increasing traction in B2B.

“Our preliminary third quarter revenue marks an important milestone for SenesTech, reaching the $1 million threshold for the first time and setting a second consecutive quarterly record,” said Michael Edell, Chief Executive Officer of SenesTech. “This is another quarter demonstrating progress on the plans and strategies we have previously announced, and our full third quarter financial results are expected to reflect that progress across the commercial model we have been building. E-commerce continues to scale as a controllable, data-driven acquisition engine, our vertical-focused B2B organization is gaining traction, and higher subscription revenue is expanding our recurring revenue base and improving the quality and visibility of revenue.”

“We still have work to do, but we believe this is a clear indication that we are on the right path. We continue to lay the foundation for a much larger company in the future by working to expand e-commerce and B2B significantly in a cost-effective manner. With many of the investments and transition costs incurred earlier in the year increasingly behind us, coupled with strong revenue growth and improved unit economics, we expect continued, improved metrics going forward,” Edell concluded.

The preliminary third quarter 2026 revenue presented in this release is unaudited, preliminary and subject to adjustment, and remains subject to completion of the Company’s quarter-end closing procedures.

About SenesTech

SenesTech is the leader in rodent birth control and sustainable rodent population management, with a mission to support a healthier environment through the responsible management of animal pest populations. The Company's Evolve® and ContraPest® fertility control solutions, along with its assessment and monitoring services, target reproduction to help reduce rodent populations. SenesTech serves consumer and professional markets with proven approaches that can be used independently or as part of an integrated pest management (IPM) program.

For more information, visit https://senestech.com.

Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are intended to be covered by the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These include statements regarding the Company’s expected third quarter 2026 revenue, anticipated momentum in e-commerce and increasing traction in B2B, expected progress across the Company’s commercial model, and anticipated continued, improved metrics going forward. Words such as “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “project,” “should,” “will” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Forward-looking statements are based on current expectations and assumptions and are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied. These risks include the risk that the Company may not realize the benefits expected from its e-commerce, B2B and subscription strategies, or be successful in commercialization of its products, realize sufficient market acceptance of its products, or capitalize on market opportunities and accelerate growth; the risks of establishing an entirely new product category, including the time, expense and uncertainty of building market awareness and customer acceptance; the risk that the Company may not be able to build and scale a professional B2B sales organization and to execute a vertical-market strategy; risks related to the Co

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Exhibit 99.1

SenesTech Reports Record Q2 2026 Revenue and Gross Margin as

E-commerce Growth Accelerates

Revenue rose 56% sequentially and gross margin reached a company-record 73.6% in the first full quarter of in-house Amazon management, advancing the Company’s intended shift to a scalable, recurring-revenue platform.

SURPRISE, Ariz., August 5, 2026 /PRNewswire/ — SenesTech, Inc. (NASDAQ: SNES), the leader in fertility control for managing animal pest populations and the only manufacturer of EPA-compliant Rodent Birth Control™ products, today announced financial results for the second quarter ended June 30, 2026.

Q2 2026 Financial Highlights

•Total revenue increased 56% to a record $770,000 in Q2 2026, compared to $493,000 in Q1 2026, and increased 23% compared to $625,000 in Q2 2025. Growth was driven by continued expansion of the Company’s e-commerce business across both online DTC and online B2B channels, led by record performance during the first full quarter of in-house Amazon management and reflecting greater control over advertising, pricing and channel economics.

•First-half 2026 revenue increased 14% year over year to a record $1.26 million, compared to $1.11 million in the first half of 2025, reflecting continued execution of the Company’s overall growth strategy and establishing the strongest first-half revenue performance in Company history.

•E-commerce revenue, which includes both online DTC and online B2B channels, more than tripled to a record $511,000 in Q2 2026, compared to $179,000 in Q1 2026, an increase of 186%, and increased 206% compared to $167,000 in Q2 2025. Growth reflected accelerating adoption of Evolve®, stronger execution across Amazon and Shopify, and continued growth in subscription customers. For the first time in the Company’s history, e-commerce revenue exceeded direct B2B revenue, reflecting the continued expansion of the Company’s online business and the growing role e-commerce is expected to play in supporting future direct B2B growth.

•Amazon revenue increased more than fivefold to a record $349,000 in Q2 2026, compared to $61,000 in Q1 2026. Q2 marked the first full quarter under Company management, with Amazon establishing new records for order count, revenue, subscription revenue and subscriber count. Prior to February 2026, Amazon was managed by a third party.

•The Company’s e-commerce website revenue increased 31% to $155,000 in Q2 2026, compared to $118,000 in Q1 2026. Record subscriber growth demonstrated the continued expansion of the Company’s e-commerce strategy across both online DTC and online B2B channels.

•DTC subscription revenue increased 89% to a record $104,000 in Q2 2026, compared to $55,000 in Q1 2026, and increased 142% compared to $43,000 in Q2 2025. Combined subscriber count across Amazon and the Company’s e-commerce website increased 117% to a record level at quarter end, further strengthening the Company’s recurring revenue base and increasing revenue visibility.

•Direct B2B revenue was $259,000 in Q2 2026, compared to $460,000 in Q2 2025, which included a $180,000 periodic bulk sale associated with third-party management of the Amazon channel, as well as a large initial stocking order from a new distributor. With the Company’s e-commerce strategy now firmly established, a new EVP of Sales has been appointed to accelerate growth across the Company’s targeted B2B verticals.

•Evolve® revenue increased 27% to $662,000 in Q2 2026, compared to $520,000 in Q2 2025, and represented 86% of product revenue, compared to 83% in Q2 2025. ContraPest® revenue increased to

$107,000 in Q2 2026, compared to $105,000 in Q2 2025, and increased 43% from $75,000 in Q1 2026, reflecting a renewed focus on select customers and markets.

•Gross profit increased 68% to a record $567,000 in Q2 2026, compared to $338,000 in Q1 2026, and increased 39% compared to $409,000 in Q2 2025. Gross profit grew faster than revenue, reflecting improved channel mix, stronger direct-channel economics and disciplined product costs.

•Gross margin increased to a company-record 73.6% in Q2 2026, compared to 68.5% in Q1 2026 and 65.5% in Q2 2025. The improvement reflected continued strength in the Company’s e-commerce business, favorable supply costs, favorable product mix and disciplined pricing practices.

•Net loss for Q2 2026 improved to $1.8 million, compared to $2.1 million in Q1 2026. Net loss increased on a year-over-year basis, compared to $1.6 million in Q2 2025. The sequential improvement reflected higher revenue and record gross profit and was achieved despite $273,000 in severance costs.

•Adjusted EBITDA loss improved 15% to $1.4 million in Q2 2026, compared to $1.6 million in Q1 2026. Adjusted EBITDA loss increased on a year-over-year basis compared to $1.2 million in Q2 2025.

•Cash and cash equivalents totaled $5.1 million at quarter end.

July 2026 E-Commerce Momentum Accelerates

•E-commerce revenue for

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Exhibit 99.1

SenesTech Active Subscriber Base More Than Doubles as E-commerce Strategy Gains Momentum

Integrated e-commerce strategy drives recurring revenue while supporting long-term growth across

consumer and business-to-business markets.

SURPRISE, Ariz., Aug. 3, 2026 — SenesTech, Inc. (NASDAQ: SNES), the leader in rodent birth control solutions, today announced that its active online subscription customer base, comprising both direct-to-consumer ("DTC") and business-to-business ("B2B") customers, more than doubled during the second quarter of 2026 compared to the first quarter, reaching a record level. That expansion reinforces the Company's recurring revenue model while potentially increasing customer lifetime value and improving long-term revenue visibility.

SenesTech's e-commerce business, which serves DTC and B2B customers placing one-time and subscription orders, grew 186% during the second quarter compared to the prior quarter. Subscriber growth was a meaningful contributor. The growth also reflects the Company's investments in Amazon, SenesTech.com and digital marketing, as well as the transition to direct management of its Amazon channel and Shopify platform.

The Company's e-commerce channels are also a meaningful source of commercial demand. A substantial portion of Shopify revenue comes from B2B customers, which the Company believes demonstrates that e-commerce demand extends well beyond the consumer market. Smaller commercial accounts increasingly purchase directly online, while larger accounts continue to be served by the Company's direct B2B sales team.

The strategy serves multiple purposes. Beyond driving direct-to-consumer sales, the Company's digital investments are intended to increase brand awareness, educate the market about rodent birth control and generate demand that supports its direct B2B sales efforts. Management believes rising consumer awareness also strengthens commercial demand by expanding brand familiarity, supporting growth across the Company's targeted vertical markets.

Building a larger active subscriber base is a key element of the Company's long-term e-commerce strategy. Subscription customers help generate predictable recurring revenue, improve visibility into future demand and strengthen long-term customer relationships. Unlike one-time product purchases, subscriptions are expected to encourage ongoing product use and create a more stable, recurring revenue stream.

The Company believes this strategy is particularly well suited for both its Evolve® and ContraPest® product lines because rodent birth control is designed for ongoing use as part of a long-term rodent population management program rather than as a one-time treatment. A subscription model simplifies replenishment for both consumer and commercial customers while encouraging consistent product use.

"Subscriber growth has become one of the clearest indicators that our e-commerce strategy is working," said Michael Edell, President and Chief Executive Officer of SenesTech. "Every new subscriber strengthens the predictability and quality of our revenue while creating long-term customer relationships. And the investments we are making in e-commerce are benefiting our entire business."

"Our e-commerce strategy is only one component of our long-term growth plan," continued Edell. "The investments we are making today are strengthening our brands, expanding recurring revenue and creating opportunities across our targeted commercial markets. As awareness continues to grow, we believe this

foundation will support sustainable growth throughout our business and further diversify our revenue base over time."

About SenesTech, Inc.

SenesTech is the leader in rodent birth control solutions. The Company's patented products, marketed under its Evolve® and ContraPest® brands, provide effective, sustainable approaches to long-term rodent population management that can be integrated into existing pest management programs or used independently. SenesTech serves both consumer and professional markets with science-based solutions aimed at addressing one of the world's most persistent pest challenges.

For more information, visit https://senestech.com.

Safe Harbor Statement

This press release contains forward-looking statements within the meaning of the federal securities laws. Forward-looking statements include, but are not limited to, statements regarding the expected benefits of the Company's e-commerce, direct-to-consumer, business-to-business and subscription strategies, including the potential for recurring customer relationships, increased customer lifetime value, future revenue visibility, future demand for Evolve® and ContraPest®, brand awareness and commercial growth. You are cautioned that such statements are based on current expectations and assumptions and are subject to risks, uncertainties and other factors that could cause actual results to differ