AI Earnings Predictions for Quantum-Si Incorporated (QSI)

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Exhibit 99.1

Quantum-Si Reports Third Quarter 2026 Financial Results and

Provides Business Update

Proteus™ remains on track for anticipated Q2 2027 commercial launch

BRANFORD, Conn., November 5, 2026 (GLOBE NEWSWIRE) — Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through single-molecule protein sequencing, today announced financial results for the third quarter ended September 30, 2026.

Press Release Highlights

•Reported third quarter 2026 revenue of $212,000 during the transition period from Platinum® to Proteus, which is expected to continue through the first half of 2027

•Highlighted interim Proteus performance data presented at World HUPO including approximately 30 times more sequencing output per chamber in a controlled peptide study

•Highlighted detection of 19 amino acids, with the 20th expected before year-end

•Announced launch of the Proteus pre-order program

•Updated full-year 2026 guidance for lower adjusted total operating expenses and lower total cash usage, and reaffirmed cash runway into the fourth quarter of 2028

“We made significant progress during the third quarter as we continued to advance Proteus toward commercial launch,” said Jeff Hawkins, President and Chief Executive Officer of Quantum-Si. “Based on recent performance data, we believe we have substantially addressed the instrument variability issues identified earlier in development, and design activities for our additional instrument cycle are now complete. During the quarter, we also advanced recognizer development to 19 amino acids, keeping us on track to achieve all 20 amino acids by year-end. We also made meaningful progress in our library preparation technology development and accelerated the integration of AI throughout our data analysis pipeline. Together, these advancements continue to strengthen the capabilities of the Proteus platform and our confidence in its commercial potential.”

Hawkins continued, “At World HUPO, we demonstrated that Proteus significantly outperformed Platinum Pro across key measures of sequencing performance. While we are encouraged by these results, we believe the Proteus platform we ultimately launch will meaningfully exceed the performance demonstrated in this interim study. Based on customer feedback and the positive reception to the data, we recently launched our Proteus pre-order program to help customers plan for adoption and secure priority access following commercial launch. We expect to provide multiple updates over the coming months and into the first half of 2027 related to system performance, commercial readiness, and customer adoption. We remain confident in our path to commercial launch of Proteus in the second quarter of 2027.”

Third Quarter 2026 Financial Results

For the third quarter of 2026, the Company recorded revenue of $212,000, compared to $552,000 in the third quarter of 2025. For the nine months ended September 30, 2026, the Company recorded revenue of $814,000, compared to $2.0 million in the prior-year period. The year-over-year decrease reflected the Company’s transition from Platinum to the anticipated Proteus platform, with 2026 and the first half of 2027 expected to

serve as the transition period. During this period, revenue is expected to reflect lower Platinum instrument demand, continued consumable usage by existing customers, customer awareness of the anticipated Proteus launch, and commercial programs intended to support customer migration to Proteus. Gross profit was $74,000 and gross margin was 35% in the third quarter of 2026 compared to gross profit of $194,000 and gross margin of 35% in the third quarter of 2025. For the nine months ended September 30, 2026, gross profit was $320,000 and gross margin was 39%, compared to gross profit of $1.0 million and gross margin of 52% in the prior-year period, with results affected by revenue mix, timing of sales, and transition-period commercial activity.

Total operating expenses were $23.9 million for the third quarter of 2026, compared to $40.0 million for the same period in the prior year, and $73.8 million for the nine months ended September 30, 2026, compared to $96.0 million for the same period in the prior year. Adjusted total operating expenses were $18.2 million for the third quarter of 2026, compared to $21.4 million for the same period in the prior year, and adjusted total operating expenses for the nine months ended September 30, 2026, were $62.1 million, compared to $68.1 million for the same period in the prior year. The year-over-year decrease in total operating expenses primarily reflected the absence of $13.6 million of net lease termination expense and $1.8 million of legal settlement expense, net of insurance proceeds, recorded in the third quarter of 2025, as well as lower selling, general and administrative expenses, partially offset by $2.9 mi

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Exhibit 99.1

Quantum-Si Reports Second Quarter 2026 Financial Results and

Provides Proteus™ Development Update

Company updates anticipated commercial launch of Proteus to Q2 2027, cost-reduction actions expected to extend cash runway into Q4 2028 and highlights estimated new market opportunities for protein sequencing

BRANFORD, Conn. -- (GLOBE NEWSWIRE) -- August 13, 2026 -- Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining protein analysis through single-molecule protein sequencing, today announced financial results for the second quarter ended June 30, 2026.

Press Release Highlights

•Reported second quarter 2026 revenue of $344 thousand during the Proteus transition period.

•Updated anticipated Proteus launch timeline to Q2 2027 to incorporate an additional integrated instrument design cycle focused on manufacturing readiness, system repeatability, and customer experience at launch.

•Highlighted an estimated $4 billion non-human proteomics market opportunity identified through on-going Platinum commercialization activities.

•Announced a reduction in force of approximately 20% of the Company’s workforce to align resources and spending with the updated Proteus launch timeline.

•Extended cash runway into Q4 2028 from Q2 2028.

“Our conviction in Proteus remains strong. Testing of our integrated instruments has generated sequencing data that reinforces our confidence in the underlying technology,” said Jeff Hawkins, president and Chief Executive Officer of Quantum-Si. “As we advanced the program, we concluded that adding an additional integrated instrument design cycle was the most responsible path to strengthen manufacturing readiness, improve system performance, and ensure a successful customer experience at launch. While this decision extends the timeline, we believe it significantly improves our readiness for commercialization and positions Proteus to create the maximum long-term value for customers, shareholders, and the broader scientific community.”

Hawkins continued, “As we continue to advance Proteus toward commercialization, our ongoing customer work is also expanding our view of the platform’s addressable markets. Over the past few months, we have been working with multiple customers applying protein sequencing to agricultural applications, pathogen detection and typing, and viral protein surveillance applications. Based on this work, we believe the non-human proteomics market opportunity for Proteus is substantial, at more than $4 billion annually and is likely to be larger as we continue to develop our understanding of additional non-human markets.”

Second Quarter 2026 Financial Results

For the second quarter of 2026, the Company recorded revenue of $344 thousand, compared to $591 thousand in the second quarter of 2025. For the six months ended June 30, 2026, the Company recorded revenue of $602 thousand, compared to $1.4 million in the prior-year period. The year-over-year decrease reflected the Company’s ongoing transition from Platinum to the anticipated Proteus platform, including lower instrument

demand, continued consumable usage by existing customers, and commercial programs intended to support customer migration to Proteus. Gross profit was $172 thousand and gross margin was 50% in the second quarter of 2026. For the six months ended June 30, 2026, gross profit was $246 thousand and gross margin was 41%, with results affected by revenue mix, timing of sales, and transition-period commercial activity.

Total operating expenses were $25.8 million for the second quarter of 2026, compared to $30.5 million for the same period in the prior year, and $49.9 million for the six months ended June 30, 2026, compared to $56.1 million for the same period in the prior year. Adjusted total operating expenses were $22.6 million for the second quarter of 2026, compared to $23.8 million for the same period in the prior year, and adjusted total operating expenses for the six months ended June 30, 2026, were $43.9 million compared to $46.6 million for the same period in the prior year. Spending levels reflected continued investment in Proteus development and commercialization readiness, partially offset by ongoing expense management.

The Company also announced cost-reduction actions, including a reduction in force affecting approximately 20% of total company headcount. The actions are expected to streamline operating expenses in connection with the revised Proteus development and launch timeline while maintaining resources for critical development, manufacturing, and commercial readiness activities. The Company expects the actions to generate approximately $12 million in annualized operating expense savings once fully implemented.

Net loss was $23.5 million for the second quarter of 2026, compared to a net loss of $28.8 million for the same period in the prior year, and net