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as of 03-06-2026 3:53pm EST

$99.24
$0.89
-0.89%
Stocks Health Care Biotechnology: Pharmaceutical Preparations Nasdaq

Nuvalent Inc is a clinical-stage biopharmaceutical company focused on creating precisely targeted therapies for patients with cancer. All of its operations are in the United States. The company is engaged in developing small molecules that are designed to overcome the limitations of existing therapies for clinically validated kinase targets. The product candidates of the company include NVL-520, which is being developed for patients with ROS1-positive non-small cell lung cancer (NSCLC), NVL-655, which is being developed for patients with anaplastic lymphoma kinase (ALK)-positive NSCLC, NVL-330, is a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to address the combined medical need of treating tumors driven by HER2ex20.

Founded: 2017 Country:
United States
United States
Employees: N/A City: CAMBRIDGE
Market Cap: 8.1B IPO Year: 2021
Target Price: $135.33 AVG Volume (30 days): 443.1K
Analyst Decision: Strong Buy Number of Analysts: 15
Dividend Yield:
N/A
Dividend Payout Frequency: N/A
EPS: -5.85 EPS Growth: -48.85
52 Week Low/High: $55.53 - $113.02 Next Earning Date: N/A
Revenue: N/A Revenue Growth: N/A
Revenue Growth (this year): N/A Revenue Growth (next year): 1064.25%
P/E Ratio: -17.10 Index: N/A
Free Cash Flow: N/A FCF Growth: N/A

AI-Powered NUVL Daily Prediction

Machine learning model trained on 25+ technical indicators

Updated a day ago

AI Recommendation

hold
Model Accuracy: 74.38%
74.38%
Confidence

Disclaimer: This prediction is generated by an AI model and should not be considered as financial advice. Always conduct your own research and consult with financial professionals before making investment decisions.

Stock Insider Trading Activity of Nuvalent Inc. (NUVL)

Miller Deborah Ann

Chief Legal Officer

Sell
NUVL Feb 26, 2026

Avg Cost/Share

$103.34

Shares

5,500

Total Value

$566,787.54

Owned After

62,436

SEC Form 4

Form 1 Form 2
Noci Darlene

Chief Development Officer

Sell
NUVL Feb 26, 2026

Avg Cost/Share

$103.44

Shares

5,500

Total Value

$566,682.00

Owned After

58,117

SEC Form 4

Form 1 Form 2
Noci Darlene

Chief Development Officer

Sell
NUVL Jan 29, 2026

Avg Cost/Share

$102.20

Shares

5,500

Total Value

$561,422.05

Owned After

58,117

SEC Form 4

Miller Deborah Ann

Chief Legal Officer

Sell
NUVL Jan 22, 2026

Avg Cost/Share

$110.16

Shares

14,300

Total Value

$1,575,288.00

Owned After

62,436

SEC Form 4

Miller Deborah Ann

Chief Legal Officer

Sell
NUVL Jan 21, 2026

Avg Cost/Share

$109.84

Shares

700

Total Value

$76,888.00

Owned After

62,436

SEC Form 4

Miller Deborah Ann

Chief Legal Officer

Sell
NUVL Jan 6, 2026

Avg Cost/Share

$97.49

Shares

2,589

Total Value

$251,559.68

Owned After

62,436

SEC Form 4

Form 1 Form 2
Noci Darlene

Chief Development Officer

Sell
NUVL Jan 6, 2026

Avg Cost/Share

$97.49

Shares

3,181

Total Value

$309,081.30

Owned After

58,117

SEC Form 4

Form 1 Form 2
Balcom Alexandra

Chief Financial Officer

Sell
NUVL Jan 6, 2026

Avg Cost/Share

$97.49

Shares

3,181

Total Value

$309,081.30

Owned After

81,733

SEC Form 4

Form 1 Form 2
Turner Christopher Durant

Chief Medical Officer

Sell
NUVL Jan 6, 2026

Avg Cost/Share

$97.49

Shares

3,181

Total Value

$309,081.30

Owned After

55,355

SEC Form 4

Form 1 Form 2
Porter James Richard

President and CEO

Sell
NUVL Jan 6, 2026

Avg Cost/Share

$97.49

Shares

9,543

Total Value

$927,243.90

Owned After

284,209

SEC Form 4

Form 1 Form 2

Earnings Transcripts

SEC 8-K filings with transcript text

View All
2025
Q4

Q4 2025 Earnings

8-K SELL

Feb 26, 2026 · 100% conf.

AI Prediction SELL

1D

-0.92%

$102.98

5D

-5.29%

$98.43

20D

+0.13%

$104.06

Price: $103.93 Prob +5D: 0% AUC: 1.000
0001193125-26-073304

8-K

0001861560false00018615602026-02-262026-02-26

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2026

NUVALENT, INC.

(Exact name of registrant as specified in its charter)

Delaware

001-40671

81-5112298

(State or other jurisdiction of incorporation)

(Commission File Number)

(I.R.S. Employer Identification No.)

Nuvalent, Inc. One Broadway, 14th Floor, Cambridge, Massachusetts 02142 (Address of principal executive offices, including zip code) (857) 357-7000 (Registrant’s telephone number, including area code) Not Applicable (Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trade Symbol(s)

Name of each exchange on which registered

Class A Common Stock, $0.0001 par value per share

NUVL

The Nasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02. Results of Operations and Financial Condition. On February 26, 2026, Nuvalent, Inc. announced its financial results for the quarter and year ended December 31, 2025, and other corporate updates. A copy of the press release issued in connection with the announcement is being furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Current Report on Form 8-K (including Exhibit 99.1 attached hereto) is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing. Item 9.01. Financial Statements and Exhibits. (d) Exhibits The following exhibit relating to Item 2.02 of this Form 8-K shall be deemed to be furnished and not filed:

Exhibit No.

Description

99.1

Press Release issued by Nuvalent, Inc. on February 26, 2026

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Nuvalent, Inc.

Date: February 26, 2026

By:

/s/ James R. Porter, Ph.D.

James R. Porter, Ph.D.

President and Chief Executive Officer

2025
Q4

Q4 2025 Earnings

8-K SELL

Jan 14, 2026 · 100% conf.

AI Prediction SELL

1D

-0.92%

$102.98

5D

-5.29%

$98.43

20D

+0.13%

$104.06

Price: $103.93 Prob +5D: 0% AUC: 1.000
0001193125-26-012243

8-K

false000186156000018615602024-01-082024-01-08

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 12, 2026

NUVALENT, INC.

(Exact name of registrant as specified in its charter)

Delaware

001-40671

81-5112298

(State or other jurisdiction of incorporation)

(Commission File Number)

(I.R.S. Employer Identification No.)

Nuvalent, Inc. One Broadway, 14th Floor, Cambridge, Massachusetts 02142 (Address of principal executive offices, including zip code) (857) 357-7000 (Registrant’s telephone number, including area code) Not Applicable (Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trade Symbol(s)

Name of each exchange on which registered

Class A Common Stock, $0.0001 par value per share

NUVL

The Nasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02.

Results of Operations and Financial Condition.

On January 12, 2026, Nuvalent, Inc. (the “Company”) issued a press release in which it reported a preliminary estimate that, as of December 31, 2025, it had approximately $1.4 billion in cash, cash equivalents and marketable securities. This amount is a preliminary, unaudited estimate only as of January 12, 2026, is subject to completion of the Company’s year-end financial closing procedures that could result in changes to the amount, and does not present all information necessary for an understanding of the Company’s financial condition as of December 31, 2025. A copy of the press release is being furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Current Report on Form 8-K (including Exhibit 99.1 attached hereto) is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.

Forward-Looking Statements

This Current Report on Form 8-K contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, implied and express statements regarding the Company’s estimate of its cash, cash equivalents and marketable securities as of December 31, 2025. Any forward-looking statements in this Current Report on Form 8-K are based on management’s current expectations and beliefs and are subject to a number of risks, uncertainties, and important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this Current Report on Form 8-K, including the risks and uncertainties described in greater detail in the section entitled “Risk Factors” in the Company’s Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2025, as well as any prior and subsequent filings with the Securities and Exchange Commission. In addition, any forward-looking statements represent the Company’s views only as of the date of this Current Report on Form 8-K and should not be relied upon as representing its views as of any subsequent date. The Company explicitly disclaims any obligation to update any forward-looking statements.

Item 9.01. Financial Statements and Exhibits. (d) Exhibits The following exhibit relating to Item 2.02 of this Form 8-K shall be deemed to be furnished and not filed:

Exhibit No.

Description

99.1

Press Release issued by Nuvalent, Inc. on January 12, 2026

104

Cover Page Interactive Data File (embedded within the Inline XBRL d

2025
Q3

Q3 2025 Earnings

8-K

Oct 30, 2025

0001193125-25-257347

8-K

false0001861560October 30, 202500018615602025-10-302025-10-30

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2025

NUVALENT, INC.

(Exact name of registrant as specified in its charter)

Delaware

001-40671

81-5112298

(State or other jurisdiction of incorporation)

(Commission File Number)

(I.R.S. Employer Identification No.)

Nuvalent, Inc. One Broadway, 14th Floor, Cambridge, Massachusetts 02142 (Address of principal executive offices, including zip code) (857) 357-7000 (Registrant’s telephone number, including area code) Not Applicable (Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trade Symbol(s)

Name of each exchange on which registered

Class A Common Stock, $0.0001 par value per share

NUVL

The Nasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02. Results of Operations and Financial Condition. On October 30, 2025, Nuvalent, Inc. announced its financial results for the quarter ended September 30, 2025, and other corporate updates. A copy of the press release issued in connection with the announcement is being furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Current Report on Form 8-K (including Exhibit 99.1 attached hereto) is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing. Item 9.01. Financial Statements and Exhibits. (d) Exhibits The following exhibit relating to Item 2.02 of this Form 8-K shall be deemed to be furnished and not filed:

Exhibit No.

Description

99.1

Press Release issued by Nuvalent, Inc. on October 30, 2025

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Nuvalent, Inc.

Date:

October 30, 2025

By:

/s/ James R. Porter, Ph.D.

James R. Porter, Ph.D. President and Chief Executive Officer

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