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AI Earnings Predictions for Heron Therapeutics Inc. (HRTX)

Machine learning predictions based on historical earnings data and price patterns

Latest Prediction

SELL

1-Day Prediction

-10.18%

$0.33

0% positive prob.

5-Day Prediction

-16.56%

$0.31

0% positive prob.

20-Day Prediction

-11.83%

$0.33

0% positive prob.

Price at prediction: $0.37 Confidence: 100.0% Model AUC: 1.0000 Quarter: Q3 2026

Historical Earnings Predictions

Quarter Signal 1D Return 5D Return 20D Return Confidence Actual 5D
Q3 2026 SELL -10.18% -16.56% -11.83% 100.0% Pending
Q2 2026 SELL -10.79% -17.81% -13.54% 100.0% Pending
Q1 2026 SELL -12.26% -18.78% -8.03% 100.0% -10.04%
Q4 2025 BUY +11.64% +25.58% +19.20% 99.9% -15.00%

Earnings Transcripts

SEC 8-K filings with transcript text

View All
2026
Q3

Q3 2026 Earnings

8-K SELL

Nov 9, 2026 · 100% conf.

AI Prediction SELL

1D

-10.18%

$0.33

Act: +0.70%

5D

-16.56%

$0.31

20D

-11.83%

$0.33

Price: $0.37 Prob +5D: 0% AUC: 1.000
0001193125-26-452721

EX-99.1

2 hrtx-ex99_1.htm

EX-99.1

EX-99.1

Exhibit 99.1

Heron Therapeutics Announces Third Quarter 2026 Financial Results

• Q3 2026 net revenue of $35.3 million; ZYNRELEF® net revenue up 13.8% and APONVIE® net revenue up 49.3% compared to the third quarter of 2025

• Entered into a definitive agreement under which CorMedix Therapeutics will acquire substantially all of Heron’s assets, announced separately today

CARY, N.C., November 9, 2026 (GLOBE NEWSWIRE) - Heron Therapeutics, Inc. (Nasdaq: HRTX) (“Heron” or the “Company”), a commercial-stage biotechnology company focused on improving the lives of patients by developing and commercializing therapeutic innovations that improve medical care, today announced financial results for the three and nine months ended September 30, 2026 and recent corporate updates.

Business Highlights

• Heron generated total net revenue of $35.3 million in Q3 2026, compared to $38.2 million in Q3 2025 and $37.7 million in Q2 2026. Heron ended the third quarter with $23.4 million in cash, cash equivalents and short-term investments.

• Acute Care franchise updates: Net revenue increased 22.5% year-over-year for the three months ended September 30, 2026 and increased 32.4% year-over-year for the nine months ended September 30, 2026. ZYNRELEF® contributed $10.6 million and $31.9 million net revenue in the three and nine months ended September 30, 2026, respectively. APONVIE® contributed $4.5 million and $12.2 million net revenue in the three and nine months ended September 30, 2026, respectively.

• Oncology Supportive Care franchise updates: Net revenue was $20.1 million in the three months ended September 30, 2026 and $63.5 million in the nine months ended September 30, 2026. CINVANTI® contributed $20.0 million and $62.3 million in the three and nine months ended September 30, 2026, respectively. Commercial sales of SUSTOL® ceased on September 30, 2026.

• Proposed asset sale: In a separate press release issued today, Heron and CorMedix Therapeutics (“CorMedix”) announced that they have entered into a definitive asset purchase agreement under which CorMedix will acquire substantially all of the assets of Heron (the “Asset Sale”). The Asset Sale is subject to approval by Heron’s stockholders and other customary closing conditions. Additional information is available in that press release and in the Current Report on Form 8-K to be filed by Heron with the Securities and Exchange Commission (“SEC”).

Financial Guidance for 2026

As previously announced, the Company withdrew its full-year 2026 financial guidance in August 2026. The Company is not providing financial guidance at this time.

1

Net Revenue Performance – Three Months Ended September 30

(in thousands)

(unaudited)

2026

2025

Dollar Change

Percentage Change

Acute Care

$ 15,128

$ 12,347

$ 2,781

22.5%

APONVIE

$ 4,530

$ 3,034

$ 1,496

49.3%

ZYNRELEF

$ 10,598

$ 9,313

$ 1,285

13.8%

Oncology

$ 20,122

$ 25,866

($ 5,744)

(22.2%)

CINVANTI

$ 19,970

$ 23,955

($ 3,985)

(16.6%)

SUSTOL

$ 152

$ 1,911

($ 1,759)

(92.0%)

Total Net Revenue

$ 35,250

$ 38,213

($ 2,963)

(7.8%)

Net Revenue Performance – Nine Months Ended September 30

(in thousands)

(unaudited)

2026

2025

Dollar Change

Percentage Change

Acute Care

$ 44,088

$ 33,300

$ 10,788

32.4%

APONVIE

$ 12,200

$ 7,758

$ 4,442

57.3%

ZYNRELEF

$ 31,888

$ 25,542

$ 6,346

24.8%

Oncology

$ 63,539

$ 81,016

($ 17,477)

(21.6%)

CINVANTI

$ 62,298

$ 73,841

($ 11,543)

(15.6%)

SUSTOL

$ 1,241

$ 7,175

($ 5,934)

(82.7%)

Total Net Revenue

$ 107,627

$ 114,316

($ 6,689)

(5.9%)

2

Conference Call and Webcast

Heron will not host a conference call or webcast in connection with its third quarter 2026 financial results.

About ZYNRELEF® for Postoperative Pain

ZYNRELEF is the first and only extended-release dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of nonsteroidal anti-inflammatory drug meloxicam. ZYNRELEF is the first and only extended-release local anesthetic to demonstrate in Phase 3 studies significantly reduced pain and significantly increased proportion of patients requiring no opioids through the first 72 hours following surgery compared to bupivacaine solution, the current standard-of-care local anesthetic for postoperative pain control. ZYNRELEF was initially approved by the FDA in May 2021 for use in adults for soft tissue or periarticular instillation to produce postsurgical analgesia for up to 72 hours after bunionectomy, open inguinal herniorrhaphy and total knee arthroplasty. In December 2021, the FDA approved an expansion of ZYNRELEF's indication to include foot and ankle, small-to-medium open abdominal, and lower extremity total joint arthroplasty surgical procedures. On January 23, 2024, the FDA approved ZYNRELEF for soft tissue and orthopedic surgical procedures including foot and ankle, and other procedures in which direct exposure to artic

2026
Q2

Q2 2026 Earnings

8-K SELL

Aug 10, 2026 · 100% conf.

AI Prediction SELL

1D

-10.79%

$0.43

Act: -4.23%

5D

-17.81%

$0.40

20D

-13.54%

$0.42

Price: $0.49 Prob +5D: 0% AUC: 1.000
0001193125-26-341300

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2026
Q1

Q1 2026 Earnings

8-K SELL

May 11, 2026 · 100% conf.

AI Prediction SELL

1D

-12.26%

$0.84

Act: +0.93%

5D

-18.78%

$0.78

Act: -10.04%

20D

-8.03%

$0.88

Act: -57.62%

Price: $0.96 Prob +5D: 0% AUC: 1.000
0001193125-26-215752

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U.S. Securities and Exchange Commission

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For best practices on efficiently downloading information from SEC.gov, including the latest EDGAR filings, visit sec.gov/developer. You can also sign up for email updates on the SEC open data program, including best practices that make it more efficient to download data, and SEC.gov enhancements that may impact scripted downloading processes. For more information, contact opendata@sec.gov.

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If a user or application submits more than 10 requests per second, further requests from the IP address(es) may be limited for a brief period. Once the rate of requests has dropped below the threshold for 10 minutes, the user may resume accessing content on SEC.gov. This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website.

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About Heron Therapeutics Inc. (HRTX) Earnings

This page provides Heron Therapeutics Inc. (HRTX) earnings call transcripts from SEC 8-K filings along with AI-powered predictions for post-earnings price movements. Our machine learning models analyze historical earnings data, pre-earnings price patterns, volume changes, and volatility to predict 1-day, 5-day, and 20-day returns after each earnings release.

Earnings transcripts are sourced directly from SEC EDGAR filings. Predictions are generated using gradient boosting models trained on HRTX's historical earnings reactions. All predicted returns are shown as percentages, and predicted prices are calculated from the closing price at the time of prediction. Past performance does not guarantee future results.

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