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as of 03-19-2026 3:42pm EST

$5.47
+$0.05
+0.92%
Stocks Health Care Biotechnology: Pharmaceutical Preparations Nasdaq

Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Its product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; ANX1502 for Oral small molecule; and ANX009, for systemic autoimmune diseases.

Founded: 2011 Country:
United States
United States
Employees: N/A City: BRISBANE
Market Cap: 730.4M IPO Year: 2020
Target Price: $16.50 AVG Volume (30 days): 2.2M
Analyst Decision: Strong Buy Number of Analysts: 6
Dividend Yield:
N/A
Dividend Payout Frequency: annual
EPS: -1.08 EPS Growth: 42.94
52 Week Low/High: $1.28 - $7.18 Next Earning Date: 03-05-2026
Revenue: N/A Revenue Growth: N/A
Revenue Growth (this year): N/A Revenue Growth (next year): N/A
P/E Ratio: -5.02 Index: N/A
Free Cash Flow: -118021000.0 FCF Growth: N/A

AI-Powered ANNX Daily Prediction

Machine learning model trained on 25+ technical indicators

Updated a day ago

AI Recommendation

hold
Model Accuracy: 78.40%
78.40%
Confidence

Disclaimer: This prediction is generated by an AI model and should not be considered as financial advice. Always conduct your own research and consult with financial professionals before making investment decisions.

Stock Insider Trading Activity of Annexon Inc. (ANNX)

Buy
ANNX Mar 10, 2026

Avg Cost/Share

$5.67

Shares

8,000

Total Value

$45,360.00

Owned After

62,405

SEC Form 4

Lew Jennifer

EVP & CHIEF FINANCIAL OFFICER

Sell
ANNX Mar 2, 2026

Avg Cost/Share

$5.42

Shares

5,565

Total Value

$30,162.30

Owned After

170,700

SEC Form 4

Overdorf Michael

EVP & CHIEF BUSINESS OFFICER

Sell
ANNX Mar 2, 2026

Avg Cost/Share

$5.42

Shares

4,339

Total Value

$23,517.38

Owned After

182,625

SEC Form 4

Dananberg Jamie

CHIEF MEDICAL OFFICER

Sell
ANNX Mar 2, 2026

Avg Cost/Share

$5.43

Shares

5,820

Total Value

$31,602.60

Owned After

123,582

SEC Form 4

ARTIS DEAN RICHARD

EVP & CHIEF SCIENTIFIC OFFICER

Sell
ANNX Mar 2, 2026

Avg Cost/Share

$5.43

Shares

5,894

Total Value

$32,004.42

Owned After

180,093

SEC Form 4

Yednock Ted

EVP & CHIEF INNOVATION OFFICER

Sell
ANNX Mar 2, 2026

Avg Cost/Share

$5.42

Shares

5,566

Total Value

$30,167.72

Owned After

154,161

SEC Form 4

Lew Jennifer

EVP & CHIEF FINANCIAL OFFICER

Sell
ANNX Feb 18, 2026

Avg Cost/Share

$5.11

Shares

7,851

Total Value

$40,118.61

Owned After

170,700

SEC Form 4

Overdorf Michael

EVP & CHIEF BUSINESS OFFICER

Sell
ANNX Feb 18, 2026

Avg Cost/Share

$5.10

Shares

6,225

Total Value

$31,747.50

Owned After

182,625

SEC Form 4

Dananberg Jamie

CHIEF MEDICAL OFFICER

Sell
ANNX Feb 18, 2026

Avg Cost/Share

$5.10

Shares

5,290

Total Value

$26,979.00

Owned After

123,582

SEC Form 4

ARTIS DEAN RICHARD

EVP & CHIEF SCIENTIFIC OFFICER

Sell
ANNX Feb 18, 2026

Avg Cost/Share

$5.10

Shares

5,290

Total Value

$26,979.00

Owned After

180,093

SEC Form 4

Earnings Transcripts

SEC 8-K filings with transcript text

View All
2025
Q3

Q3 2025 Earnings

8-K BUY

Nov 10, 2025 · 100% conf.

AI Prediction BUY

1D

+7.21%

$3.19

Act: -0.34%

5D

+14.53%

$3.41

Act: +1.34%

20D

+4.40%

$3.11

Act: +63.09%

Price: $2.98 Prob +5D: 100% AUC: 1.000
0001193125-25-274220

8-K

false000152811500015281152025-11-102025-11-10

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 10, 2025

ANNEXON, INC.

(Exact name of registrant as specified in its charter)

Delaware

001-39402

27-5414423

(State or other jurisdiction

(Commission

(IRS Employer

of incorporation)

File Number)

Identification No.)

1400 Sierra Point Parkway, Bldg C, Suite 200 Brisbane, California 94005 (Address of principal executive offices) (Zip Code)

Registrant’s telephone number, including area code: (650) 822-5500 Not Applicable (Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, par value $0.001 per share

ANNX

The Nasdaq Stock Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02. Results of Operations and Financial Condition. On November 10, 2025, Annexon, Inc. (the “Company”) announced certain financial results for the third quarter ended September 30, 2025. A copy of the Company’s press release, titled “Annexon Reports Third Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated Milestones” is furnished pursuant to Item 2.02 as Exhibit 99.1 hereto. The information in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Section 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing, except as expressly set forth by specific reference in such a filing. Item 9.01. Financial Statements and Exhibits. (d)Exhibits.

Exhibit

Description

99.1

Press Release, dated November 10, 2025, titled “Annexon Reports Third Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated Milestones”

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Dated: November 10, 2025

Annexon, Inc.

By:

/s/ Jennifer Lew

Jennifer Lew

Executive Vice President and Chief Financial Officer

2025
Q2

Q2 2025 Earnings

8-K

Aug 14, 2025

0000950170-25-108859

8-K

false000152811500015281152025-08-142025-08-14

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 14, 2025

ANNEXON, INC.

(Exact name of registrant as specified in its charter)

Delaware

001-39402

27-5414423

(State or other jurisdiction

(Commission

(IRS Employer

of incorporation)

File Number)

Identification No.)

1400 Sierra Point Parkway, Bldg C, Suite 200 Brisbane, California 94005 (Address of principal executive offices) (Zip Code)

Registrant’s telephone number, including area code: (650) 822-5500 Not Applicable (Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, par value $0.001 per share

ANNX

The Nasdaq Stock Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02. Results of Operations and Financial Condition. On August 14, 2025, Annexon, Inc. (the “Company”) announced certain financial results for the second quarter ended June 30, 2025. A copy of the Company’s press release, titled “Annexon Reports Second Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated Milestones” is furnished pursuant to Item 2.02 as Exhibit 99.1 hereto. The information in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Section 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing, except as expressly set forth by specific reference in such a filing. Item 9.01. Financial Statements and Exhibits. (d)Exhibits.

Exhibit

Description

99.1

Press Release, dated August 14, 2025, titled “Annexon Reports Second Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated Milestones”

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Dated: August 14, 2025

Annexon, Inc.

By:

/s/ Jennifer Lew

Jennifer Lew

Executive Vice President and Chief Financial Officer

2025
Q1

Q1 2025 Earnings

8-K

May 12, 2025

0000950170-25-069156

8-K

false000152811500015281152025-05-122025-05-12

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 12, 2025

ANNEXON, INC.

(Exact name of registrant as specified in its charter)

Delaware

001-39402

27-5414423

(State or other jurisdiction

(Commission

(IRS Employer

of incorporation)

File Number)

Identification No.)

1400 Sierra Point Parkway, Bldg C, Suite 200 Brisbane, California 94005 (Address of principal executive offices) (Zip Code)

Registrant’s telephone number, including area code: (650) 822-5500 Not Applicable (Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, par value $0.001 per share

ANNX

The Nasdaq Stock Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02. Results of Operations and Financial Condition. On May 12, 2025, Annexon, Inc. (the “Company”) announced certain financial results for the first quarter ended March 31, 2025. A copy of the Company’s press release, titled “Annexon Reports First Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated Milestones” is furnished pursuant to Item 2.02 as Exhibit 99.1 hereto. The information in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Section 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing, except as expressly set forth by specific reference in such a filing. Item 9.01. Financial Statements and Exhibits. (d)Exhibits.

Exhibit

Description

99.1

Press Release, dated May 12, 2025, titled “Annexon Reports First Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated Milestones”

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Dated: May 12, 2025

Annexon, Inc.

By:

/s/ Jennifer Lew

Jennifer Lew

Executive Vice President and Chief Financial Officer

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