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as of 03-06-2026 3:41pm EST

$27.49
$0.19
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Stocks Health Care Biotechnology: Pharmaceutical Preparations Nasdaq

Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236, and others.

Founded: 2007 Country:
United States
United States
Employees: N/A City: CAMBRIDGE
Market Cap: 1.6B IPO Year: 2013
Target Price: $37.63 AVG Volume (30 days): 791.9K
Analyst Decision: Buy Number of Analysts: 8
Dividend Yield:
N/A
Dividend Payout Frequency: N/A
EPS: -7.12 EPS Growth: -161.17
52 Week Low/High: $22.24 - $46.00 Next Earning Date: 05-15-2026
Revenue: $43,011,000 Revenue Growth: N/A
Revenue Growth (this year): 75.68% Revenue Growth (next year): 167.63%
P/E Ratio: -3.90 Index: N/A
Free Cash Flow: -377293000.0 FCF Growth: N/A

AI-Powered AGIO Daily Prediction

Machine learning model trained on 25+ technical indicators

Updated 2 days ago

AI Recommendation

hold
Model Accuracy: 79.87%
79.87%
Confidence

Disclaimer: This prediction is generated by an AI model and should not be considered as financial advice. Always conduct your own research and consult with financial professionals before making investment decisions.

Stock Insider Trading Activity of Agios Pharmaceuticals Inc. (AGIO)

Washburn Theodore James Jr.

Principal Accounting Officer

Sell
AGIO Mar 3, 2026

Avg Cost/Share

$28.88

Shares

5,272

Total Value

$152,255.36

Owned After

868

SEC Form 4

Washburn Theodore James Jr.

Principal Accounting Officer

Sell
AGIO Mar 2, 2026

Avg Cost/Share

$28.96

Shares

2,223

Total Value

$64,378.08

Owned After

868

SEC Form 4

Form 1 Form 2
Gheuens Sarah

Chief Medical Officer

Sell
AGIO Mar 2, 2026

Avg Cost/Share

$28.96

Shares

4,055

Total Value

$117,432.80

Owned After

74,406

SEC Form 4

Form 1 Form 2
Goff Brian

Chief Executive Officer

Sell
AGIO Mar 2, 2026

Avg Cost/Share

$28.96

Shares

18,055

Total Value

$522,872.80

Owned After

164,548

SEC Form 4

Form 1 Form 2
Burns James William

Chief Legal Officer

Sell
AGIO Mar 2, 2026

Avg Cost/Share

$28.96

Shares

5,218

Total Value

$151,113.28

Owned After

44,086

SEC Form 4

Milanova Tsveta

Chief Commercial Officer

Sell
AGIO Mar 2, 2026

Avg Cost/Share

$28.96

Shares

2,868

Total Value

$83,057.28

Owned After

41,591

Jones Cecilia

Chief Financial Officer

Sell
AGIO Mar 2, 2026

Avg Cost/Share

$28.96

Shares

5,035

Total Value

$145,813.60

Owned After

49,328

SEC Form 4

Milanova Tsveta

Chief Commercial Officer

Sell
AGIO Jan 5, 2026

Avg Cost/Share

$27.02

Shares

2,872

Total Value

$77,601.44

Owned After

41,591

SEC Form 4

Earnings Transcripts

SEC 8-K filings with transcript text

View All
2025
Q4

Q4 2025 Earnings

8-K BUY

Feb 12, 2026 · 100% conf.

AI Prediction BUY

1D

+0.71%

$28.27

5D

+11.36%

$31.26

20D

+12.31%

$31.53

Price: $28.07 Prob +5D: 100% AUC: 1.000
0001439222-26-000023

agio-202602120001439222FALSE00014392222026-02-122026-02-12

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 12, 2026

Agios Pharmaceuticals, Inc. (Exact Name of Registrant as Specified in Charter)

Delaware 001-36014 26-0662915 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Employer Identification No.)

88 Sidney Street, Cambridge,MA 02139 (Address of Principal Executive Offices) (Zip Code)

Registrant’s telephone number, including area code: (617) 649-8600

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each classTrading symbol(s)Name of each exchange on which registered Common Stock, Par Value $0.001 per shareAGIONasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02Results of Operations and Financial Condition.

On February 12, 2026, Agios Pharmaceuticals, Inc. issued a press release announcing its results for the quarter and year ended December 31, 2025 and other business highlights. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

Item 9.01Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.Description 99.1Press release issued February 12, 2026

104Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

AGIOS PHARMACEUTICALS, INC.

Date: February 12, 2026 By: /s/ Brian Goff Brian Goff Chief Executive Officer

2025
Q3

Q3 2025 Earnings

8-K

Oct 30, 2025

0001439222-25-000114

agio-202510300001439222FALSE00014392222025-10-302025-10-30

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2025

Agios Pharmaceuticals, Inc. (Exact Name of Registrant as Specified in Charter)

Delaware 001-36014 26-0662915 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Employer Identification No.)

88 Sidney Street, Cambridge,MA 02139 (Address of Principal Executive Offices) (Zip Code)

Registrant’s telephone number, including area code: (617) 649-8600

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each classTrading symbol(s)Name of each exchange on which registered Common Stock, Par Value $0.001 per shareAGIONasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02Results of Operations and Financial Condition.

On October 30, 2025, Agios Pharmaceuticals, Inc. issued a press release announcing its results for the quarter ended September 30, 2025 and other business highlights. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

Item 9.01Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.Description 99.1Press release issued October 30, 2025

104Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

AGIOS PHARMACEUTICALS, INC.

Date: October 30, 2025 By: /s/ Brian Goff Brian Goff Chief Executive Officer

2025
Q2

Q2 2025 Earnings

8-K

Jul 31, 2025

0001439222-25-000087

agio-202507310001439222FALSE00014392222025-07-312025-07-31

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025

Agios Pharmaceuticals, Inc. (Exact Name of Registrant as Specified in Charter)

Delaware 001-36014 26-0662915 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Employer Identification No.)

88 Sidney Street, Cambridge,MA 02139 (Address of Principal Executive Offices) (Zip Code)

Registrant’s telephone number, including area code: (617) 649-8600

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) ☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) ☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) ☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each classTrading symbol(s)Name of each exchange on which registered Common Stock, Par Value $0.001 per shareAGIONasdaq Global Select Market

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02Results of Operations and Financial Condition.

On July 31, 2025, Agios Pharmaceuticals, Inc. issued a press release announcing its results for the quarter ended June 30, 2025 and other business highlights. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

Item 9.01Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.Description 99.1Press release issued July 31, 2025

104Cover Page Interactive Data File (embedded within the Inline XBRL document)

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

AGIOS PHARMACEUTICALS, INC.

Date: July 31, 2025 By: /s/ Brian Goff Brian Goff Chief Executive Officer

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