Orbimed Advisors Llc

10% Owner of XTNT

Director10% Owner of EWTX

Director of IRON

Stock Insider Trading Activity of Orbimed Advisors Llc

Name	Ticker	Relationship	Date	Transaction	AVG Cost Per Share	Shares	Total Value	Securities Owned After Transaction(s)	SEC Form 4
ORBIMED ADVISORS LLC	XTNT	10% Owner	Apr 10 '25	Sell	$0.42	73,114,592	$30,708,128.64	0	SEC Form 4 SEC Form 4
ORBIMED ADVISORS LLC	EWTX	Director10% Owner	Apr 3 '25	Buy	$20.13	496,771	$10,000,000.23	14,809,075	SEC Form 4 SEC Form 4
ORBIMED ADVISORS LLC	IRON	Director	Mar 24 '25	Sell	$54.11	5,738	$310,483.18	482,308	SEC Form 4 SEC Form 4 SEC Form 4