| Name | Ticker | Relationship | Date | Transaction | AVG Cost Per Share | Shares | Total Value | Securities Owned After Transaction(s) | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| MPM BioVentures 2014, L.P. | HOWL | 10% Owner | Oct 29 '25 | Sell | $1.55 | 134,240 | $208,072.00 | 6,442,653 | |
| MPM BioVentures 2014, L.P. | HOWL | 10% Owner | Oct 28 '25 | Sell | $1.64 | 69,068 | $113,271.52 | 6,442,653 | |
| MPM BioVentures 2014, L.P. | HOWL | 10% Owner | Oct 27 '25 | Sell | $1.72 | 72,709 | $125,059.48 | 6,442,653 |