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Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.
Orrstown Financial Services Inc is a holding company engaged in commercial banking and trust business, this involves accepting demand, time, and savings deposits and granting loans. The company is also engaged in lending services for commercial, residential, commercial mortgages, construction, municipal, and various forms of consumer lending, and deposit services that include checking, savings, time, and money market deposits. It also provides investment and brokerage services through its Financial Advisors division. The Company earns fees from its deposit clients for transaction-based account maintenance and overdraft services, It also earns wealth management and investment brokerage fees from its contracts with trusts. The company operates in a segment, namely Community Banking.