TTE vs VRTX Comparison

TotalEnergies is an integrated oil and gas company that explores for, produces, and refines oil around the world. In 2023, it produced 1.6 million barrels of liquids and 5.0 billion cubic feet of natural gas per day. At end-2023, reserves stood at 10.6 billion barrels of oil equivalent, 56% of which are liquids. During 2023, it had LNG sales of 44.3 metric tons. The company owns interests in refineries with capacity of nearly 2.0 million barrels a day, primarily in Europe, distributes refined products in 65 countries, and manufactures commodity and specialty chemicals. At year-end, its gross installed renewable power generation capacity was 22.4 gigawatts.

Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease. Additionally, Vertex is evaluating small-molecule inhibitors targeting acute and chronic pain using nonopioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.