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PEN vs IONS Comparison

Compare PEN & IONS Stocks: Price Trends, ML Decisions, Charts, Trends, Technical Analysis and more.

Logo Penumbra Inc.

PEN

Penumbra Inc.

HOLD

Current Price

$317.71

Market Cap

12.6B

Sector

Health Care

ML Signal

HOLD

IONS

Ionis Pharmaceuticals Inc.

HOLD

Current Price

$44.80

Market Cap

12.1B

Sector

Health Care

ML Signal

HOLD

Company Overview

Basic Information
Metric
PEN
IONS
Founded
2004
1989
Country
United States
United States
Employees
N/A
N/A
Industry
Medical/Dental Instruments
Biotechnology: Pharmaceutical Preparations
Sector
Health Care
Health Care
Exchange
Nasdaq
Nasdaq
Market Cap
12.6B
12.1B
IPO Year
2015
1996

Fundamental Metrics

Financial Performance
Metric
PEN
IONS
Price
$317.71
$44.80
Analyst Decision
Hold
Strong Buy
Analyst Count
16
22
Target Price
$360.14
$93.36
AVG Volume (30 Days)
277.5K
3.3M
Earning Date
05-12-2026
04-29-2026
Dividend Yield
N/A
N/A
EPS Growth
1155.56
21.71
EPS
1.70
N/A
Revenue
$1,403,665,000.00
N/A
Revenue This Year
$14.34
N/A
Revenue Next Year
$13.71
$77.99
P/E Ratio
$186.85
N/A
Revenue Growth
17.50
N/A
52 Week Low
$221.26
$44.27
52 Week High
$362.41
$86.74

Technical Indicators

Market Signals
Indicator
PEN
IONS
Relative Strength Index (RSI) 38.37 26.28
Support Level $315.31 N/A
Resistance Level $320.45 $78.11
Average True Range (ATR) 1.86 2.40
MACD -0.37 -1.43
Stochastic Oscillator 10.40 3.36

Price Performance

Historical Comparison
PEN
IONS

About PEN Penumbra Inc.

Domiciled in the US, Penumbra designs, manufactures, and markets an array of thrombectomy and embolization devices and equipment to mechanically remove blood clots. The firm sells mainly to hospitals and physicians. These minimally invasive devices are primarily used in the acute care setting for patients with stroke, pulmonary embolism, deep vein thrombosis, cranial aneurysms, and other vascular diseases.

About IONS Ionis Pharmaceuticals Inc.

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE).

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