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Day One Biopharmaceuticals Inc is a clinical-stage biopharmaceutical company. It is dedicated towards developing and commercializing targeted therapies for patients of all ages with genetically defined cancers. Initially, it focuses on clinical development efforts on pediatric patients living with cancer, a vulnerable population that has been underserved in the recent revolution in targeted therapeutics and immuno-oncology. The product candidate, DAY101, is an oral, brain-penetrant, highly-selective type II pan-rapidly accelerated fibrosarcoma, or pan-RAF, kinase inhibitor.
MRC Global Inc distributes pipes, valves, fittings, and related products and services to the energy industry. Products are often used in the construction, maintenance, repair, and overhaul of equipment used in extreme operating conditions. In these conditions and other environments, MRC's valve products give the customer the ability to control the direction, velocity, and pressure of fluids and gases within transmission networks. In addition, other products can be used to regulate flow and on/off service. MRC's other products, which include pipe, steel fitting, and tubular goods, are used across all of the industries in which the company operates. Specialized services are delivered alongside this array of products to enhance the client relationship.