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Cogent Biosciences Inc a biotechnology company focused on developing precision therapies for genetically defined diseases. It designs rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its program CGT9486, is a selective tyrosine kinase inhibitor designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. In the vast majority of cases, KIT D816V is responsible for driving Systemic Mastocytosis (SM), a serious disease caused by the unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling.
First Bancshares Inc operates as a bank holding company. It offers various products and services such as deposit, including checking accounts, savings accounts, and time deposits account for individuals, businesses, associations and organizations, and governmental authorities. It also provides commercial and personal loans, including secured and unsecured loans, consumer loans, and loans for business expansion and purchase of equipment and machinery, and residential mortgage loans. The bank renders services like financial and wealth management, online internet banking, voice response telephone inquiry, safe deposit boxes, traveler's checks, and mobile deposit, and others. It operates in the Commercial/Retail Bank, Mortgage Banking, and Holding company segments.