COGT vs ASIX Comparison

Cogent Biosciences Inc a biotechnology company focused on developing precision therapies for genetically defined diseases. It designs rational precision therapies that treat the underlying cause of disease and improve the lives of patients. Its program CGT9486, is a selective tyrosine kinase inhibitor designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. In the vast majority of cases, KIT D816V is responsible for driving Systemic Mastocytosis (SM), a serious disease caused by the unchecked proliferation of mast cells. Exon 17 mutations are also found in patients with advanced gastrointestinal stromal tumors (GIST), a type of cancer with strong dependence on oncogenic KIT signaling.

AdvanSix Inc. is an integrated manufacturer of Nylon 6, a polymer resin and fertilizers. Nylon 6 is a synthetic material used by customers to produce engineered plastics, fibers, filaments, and films, which in turn are used in such end-products as automotive and electronic components, carpets, sports apparel, fishing nets, and food and industrial packaging. In addition, it also sells a variety of other products, all of which are produced as part of the Nylon 6 resin manufacturing process including caprolactam, ammonium sulfate fertilizers, and other chemical intermediates. Geographically, the group operates through the United States and its business is also expanding internationally but it derives the majority of its revenue from the United States region.