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Biogen and Idec merged in 2003, combining forces to market Biogen's multiple sclerosis drug Avonex and Idec's cancer drug Rituxan. Today, Rituxan and next-generation antibody Gazyva (oncology) and Ocrevus (multiple sclerosis) are marketed via a collaboration with Roche. Biogen markets several multiple sclerosis drugs including Plegridy, Tysabri, Tecfidera, and Vumerity. Biogen's newer products include Spinraza (SMA, with partner Ionis), Leqembi (Alzheimers, with partner Eisai), Skyclarys (Friedreich's Ataxia, Reata), Zurzuvae (postpartum depression, Sage), and Qalsody (ALS, Ionis). Biogen has several drug candidates in phase 3 trials in neurology, immunology, and rare diseases.
Based in New York City, Tapestry is the parent company of accessories and fashion brand Coach, which accounts for about 80% of its sales and more than 90% of its operating profit. Coach products are sold through 900 company-owned stores, e-commerce, and third-party stores in North America, Asia, and Europe. Tapestry also owns Kate Spade, which generated 54% of its sales from handbags in fiscal 2024. Kate Spade is known for its colorful patterns and graphics. Meanwhile, Tapestry's smallest brand, luxury footwear maker Stuart Weitzman, is set to be sold to Caleres in the summer of 2025.