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Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company focused on discovering and developing novel therapies for the treatment of fibrosis and related diseases. Its primary product candidate is bexotegrast (PLN-74809), an oral, small molecule, that the company is developing for the treatment of idiopathic pulmonary fibrosis, or IPF, and primary sclerosing cholangitis.

Founded: 2015 Country:
United States
United States
Employees: N/A City: SOUTH SAN FRANCISCO
Market Cap: 79.9M IPO Year: 2020
Target Price: $3.75 AVG Volume (30 days): 621.1K
Analyst Decision: Hold Number of Analysts: 9
Dividend Yield:
N/A
Dividend Payout Frequency: semi-annual
EPS: -2.05 EPS Growth: -26.18
52 Week Low/High: $1.09 - $1.95 Next Earning Date: N/A
Revenue: N/A Revenue Growth: -100.00%
Revenue Growth (this year): N/A Revenue Growth (next year): N/A
P/E Ratio: -0.65 Index: N/A
Free Cash Flow: -159351000.0 FCF Growth: N/A

Stock Insider Trading Activity of Pliant Therapeutics Inc. (PLRX)

Coulie Bernard

President and CEO

Sell
PLRX Jan 20, 2026

Avg Cost/Share

$1.28

Shares

89,375

Total Value

$114,400.00

Owned After

505,601

SEC Form 4

Cummings Keith Lamont

Chief Financial Officer

Sell
PLRX Jan 20, 2026

Avg Cost/Share

$1.28

Shares

24,002

Total Value

$30,722.56

Owned After

297,214

SEC Form 4

Cheung Lily

Chief Human Resource Officer

Sell
PLRX Jan 20, 2026

Avg Cost/Share

$1.28

Shares

7,534

Total Value

$9,643.52

Owned After

44,847

SEC Form 4

Kuo Minnie

Chief Operating Officer

Sell
PLRX Jan 20, 2026

Avg Cost/Share

$1.28

Shares

6,917

Total Value

$8,853.76

Owned After

37,806

SEC Form 4

Earnings Transcripts

SEC 8-K filings with transcript text

View All
2025
Q3

Q3 2025 Earnings

8-K BUY

Nov 6, 2025 · 100% conf.

AI Prediction BUY

1D

+1.21%

$1.57

5D

+6.36%

$1.65

20D

-2.61%

$1.51

Price: $1.55 Prob +5D: 100% AUC: 1.000
0001746473-25-000173

plrx-202511060001746473FALSE00017464732025-11-062025-11-060001746473plrx:CommonStockParValue0.0001PerShareMember2025-11-062025-11-060001746473plrx:SeriesAJuniorParticipatingPreferredPurchaseRightsMember2025-11-062025-11-06

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549


FORM 8-K


CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 6, 2025


PLIANT THERAPEUTICS, INC.

(Exact name of Registrant as Specified in Its Charter)


Delaware001-3930347-4272481 (State or Other Jurisdiction of Incorporation) (Commission File Number)(IRS Employer Identification No.)

331 Oyster Point Blvd., South San Francisco, CA 94080 (Address of Principal Executive Offices) (Zip Code)

Registrant’s Telephone Number, Including Area Code: (650) 481-6770 Not Applicable (Former Name or Former Address, if Changed Since Last Report)


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each classTrading Symbol(s) Name of each exchange on which registered Common Stock, par value $0.0001 per sharePLRXThe Nasdaq Stock Market LLC Series A Junior Participating Preferred Purchase RightsN/AThe Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02    Results of Operations and Financial Condition.

On November 6, 2025, Pliant Therapeutics, Inc. (the "Company") issued a press release announcing the Company’s financial results for the third quarter ended September 30, 2025. A copy of this press release is furnished as Exhibit 99.1 to this report. The information in this Current Report on Form 8-K including the exhibits furnished herewith shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (as amended, the "Exchange Act") or otherwise subject to the liabilities of that Section, and shall not be or be deemed to be incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, regardless of any general incorporation language in such filing.

Item 9.01     Financial Statements and Exhibits. (d) Exhibits.

Exhibit No. Description 99.1 Press Release issued by the Company dated November 6, 2025

104Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

PLIANT THERAPEUTICS, INC.

Date: November 6, 2025 By:/s/ Keith Cummings Keith Cummings, M.D., MBA Chief Financial Officer

2025
Q1

Q1 2025 Earnings

8-K

May 8, 2025

0001746473-25-000097

plrx-202505080001746473FALSE00017464732024-11-072024-11-07

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549


FORM 8-K


CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025


PLIANT THERAPEUTICS, INC.

(Exact name of Registrant as Specified in Its Charter)


Delaware001-3930347-4272481 (State or Other Jurisdiction of Incorporation) (Commission File Number)(IRS Employer Identification No.)

331 Oyster Point Blvd., South San Francisco, CA 94080 (Address of Principal Executive Offices) (Zip Code)

Registrant’s Telephone Number, Including Area Code: (650) 481-6770 Not Applicable (Former Name or Former Address, if Changed Since Last Report)


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each classTrading Symbol(s) Name of each exchange on which registered Common Stock, par value $0.0001 per sharePLRXThe Nasdaq Stock Market LLC Series A Junior Participating Preferred Purchase RightsN/AThe Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02    Results of Operations and Financial Condition. On May 8, 2025, Pliant Therapeutics, Inc. (the "Company") issued a press release announcing the Company’s financial results for the first quarter ended March 31, 2025. A copy of this press release is furnished as Exhibit 99.1 to this report. The information in this Current Report on Form 8-K including the exhibits furnished herewith shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (as amended, the "Exchange Act") or otherwise subject to the liabilities of that Section, and shall not be or be deemed to be incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, regardless of any general incorporation language in such filing.

Item 9.01     Financial Statements and Exhibits. (d) Exhibits.

Exhibit No. Description 99.1 Press Release issued by the Company dated May 8, 2025

104Cover Page Interactive Data File (embedded within the Inline XBRL document).

1

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

PLIANT THERAPEUTICS, INC.

Date: May 8, 2025 By:/s/ Keith Cummings Keith Cummings, M.D., MBA Chief Financial Officer

2

2024
Q4

Q4 2024 Earnings

8-K

Mar 3, 2025

0001746473-25-000051

plrx-202503030001746473FALSE00017464732025-03-032025-03-03

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549


FORM 8-K


CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2025


PLIANT THERAPEUTICS, INC.

(Exact name of Registrant as Specified in Its Charter)


Delaware001-3930347-4272481 (State or Other Jurisdiction of Incorporation) (Commission File Number)(IRS Employer Identification No.)

331 Oyster Point Boulevard, South San Francisco, CA 94080 (Address of Principal Executive Offices) (Zip Code)

Registrant’s Telephone Number, Including Area Code: (650) 481-6770 Not Applicable (Former Name or Former Address, if Changed Since Last Report)


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class Trading Symbol(s) Name of each exchange on which registered Common Stock, par value $0.0001 per share PLRX The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter). Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 2.02    Results of Operations and Financial Condition. On March 3, 2025, Pliant Therapeutics, Inc. (the "Company") issued a press release announcing the Company’s financial results for the fourth quarter ended December 31, 2024. A copy of this press release is furnished as Exhibit 99.1 to this report. The information in this Current Report on Form 8-K including the exhibits furnished herewith shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 (as amended, the "Exchange Act") or otherwise subject to the liabilities of that Section, and shall not be or be deemed to be incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, regardless of any general incorporation language in such filing.

Item 9.01     Financial Statements and Exhibits. (d) Exhibits.

Exhibit No. Description 99.1 Press Release issued by the Company dated March 3, 2025

104Cover Page Interactive Data File (embedded within the Inline XBRL document).

1

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

PLIANT THERAPEUTICS, INC.

Date: March 3, 2025 By:/s/ Keith Cummings Keith Cummings, M.D., MBA Chief Financial Officer

2

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